New strategies against Stenotrophomonas maltophilia: a serious worldwide intrinsically drug-resistant opportunistic pathogen

作者：Brooke Joanna S^*

来源：Expert Review of Anti-Infective Therapy, 2014, 12(1): 1-4.

DOI：10.1586/14787210.2014.864553

• cystic fibrosis
• levofloxacin
• multidrug resistant
• respiratory pathogen
• Stenotrophomonas maltophilia
• ticarcillin/clavulanate
• tigecycline
• trimethroprim-sulfamethoxazole

Stenotrophomonas maltophilia is a worldwide human opportunistic pathogen associated with serious infections in humans, and is most often recovered from respiratory tract infections. In addition to its intrinsic drug resistance, this organism may acquire resistance via multiple molecular mechanisms. New antimicrobial strategies are needed to combat S. maltophilia infections, particularly in immunocompromised patients, cystic fibrosis patients with polymicrobial infections of the lung, and in patients with chronic infections. This editorial reports on newer drugs and antimicrobial strategies and their potential for use in treatment of S. maltophilia infections, the development of new technologies to detect this organism, and identifies strategies currently in use to reduce transmission of this pathogen.

• 出版日期2014-1