Diastereoselective addition of some carbanions to an optically active trifluoromethyl imine derivative

作者：Kagawa Takumi^*; Fujita Kana; Kawada Kosuke

来源：Journal of Fluorine Chemistry, 2013, 152: 77-80.

DOI：10.1016/j.jfluchem.2013.03.019

• Trifluoromethyl 2-Ethoxy-1-phenylethyl-1-imine Trifluoroacetaldehyde
• Hetero Diels-Alder addition
• Mannich reaction
• Diastereoselective synthesis

Optically active trifluoromethyl 2-ethoxy-1-phenylethyl -1-imine can react with various carbanions diastereoselectively, and in hetero Diels-Alder addition and in Mannich reaction, it can be derived to the corresponding products with high optical purity.

• 出版日期2013-8