An Efficient One-Step Synthesis of 1H-pyrazolo[3,4-b]pyridines in Basic Ionic Liquid [bmim]OH

作者：Zhao Ling ling; Wan Yu; Wang Hai ying; Wang Chao; Zhang Xiao xiao; Huang Shu ying; Liu Gui xiang; Chen Liang feng; Wu Hui^*

来源：Letters in Organic Chemistry, 2012, 9(9): 671-676.

• Basic ionic liquid
• pyrazolo[3,4-b]pyridines

Chain 1,3-dicarbonyl compounds were firstly used as starting material to react with 5-amino-3-methyl-1-phenylpyrazol and aromatic aldehydes to prepare 1H-pyrazolo[3,4-b]pyridines in basic ionic liquid [bmim]OH. The one-step three-component reaction is simple and efficient. Additionally, water was the only one by-product during the whole process.

• 出版日期2012-11