Adenoid cystic carcinoma of the minor salivary glands: a retrospective series of 29 cases and review of the literature

作者：Shum Jonathan W^*; Chatzistefanou Ioannis; Qaisi Mohammed; Lubek Joshua E; Ord Robert A

来源：Oral Surgery Oral Medicine Oral Pathology Oral Radiology, 2016, 121(3): 210-214.

DOI：10.1016/j.oooo.2015.10.003

Objective. Approximately 78% of minor salivary gland tumors are malignant, of which adenoid cystic carcinoma (ACC) represents 15% in our series. ACC is an uncommon tumor characterized by slow growth and a high potential for recurrence. This series of 29 consecutive patients examines clincopathologic features, management, and survival outcomes.
Materials and Methods. This study is a retrospective chart review of 29 patients with ACC of the minor salivary glands in a period of 23 years (1989 and 2012).
Results. The mean age was 61.2 years (16-89 years), with no gender predilection. The majority occurred in the palate/maxilla (66%) and initial presentation was stage IV. Mean follow-up was 42.6 months. Recurrence rate was 10% local, 14% distant over the observation period.
Conclusions. The palate/maxilla is the preferred location for occurrence, and initial presentation at stage IV is common. Postoperative radiation remains a common strategy to prevent local recurrence in lesions with adverse features.

• 出版日期2016-3