Alternative and expedient asymmetric syntheses of L-(+)-noviose

作者：Hanessian Stephen^*; Auzzas Luciana

来源：Organic Letters, 2008, 10(2): 261-264.

DOI：10.1021/ol702655c

L-(+)-Noviose, the sugar component of the antibiotic novobiocin, was synthesized from readily available non-carbohydrate starting materials relying on stoichiometric and asymmetric processes by two independent methods, comprising six and nine steps, in 27 and 20% overall yields, respectively.

• 出版日期2008-1-17