Acute Pancreatitis Induced by Methimazole Treatment in a 51-Year-Old Korean Man: A Case Report

作者:Jung Jung Hwa; Hahm Jong Ryeal*; Jung Jaehoon; Kim Soo Kyoung; Kim Sungsu; Kim Kyong Young; Kim Bo Ra; Kim Hong Jun; Jeong Yi Yeong; Kim Sun Joo
来源:Journal of Korean Medical Science, 2014, 29(8): 1170-1173.
DOI:10.3346/jkms.2014.29.8.1170

摘要

Methimazole (MMI)-induced acute pancreatitis is very rare but severe adverse reaction. A 51-yr-old male developed a high fever, chills, and abdominal pain, two weeks after commencement on MMI for the treatment of Graves%26apos; disease. There was no evidence of agranulocytosis, and fever subsided soon after stopping MMI treatment. However, 5 hr after taking an additional dose of MMI, abdominal pain and fever developed again. His symptoms, biochemical, and imaging studies were compatible with acute pancreatitis. After withdrawal of MMI, he showed clinical improvement. This is the first case of MMI-induced acute pancreatitis in Korea. Clinicians should be aware of the rare but possible MMI-induced pancreatitis in patients complaining of fever and abdominal pain.

  • 出版日期2014-8