Autologous serum and plasma rich in growth factors in ophthalmology: preclinical and clinical studies

作者：Anitua Eduardo; Muruzabal Francisco; Tayebba Ali; Riestra Ana; Perez Victor L; Merayo Lloves Jesus; Orive Gorka^*

来源：Acta Ophthalmologica, 2015, 93(8): E605-E614.

DOI：10.1111/aos.12710

• autologous serum
• cornea
• dry eye
• eye
• ocular surface
• plasma rich in growth factors
• platelet-rich plasma

The use of blood derivatives represents an alternative therapeutic approach that is gaining interest in regenerative medicine due to its potential to stimulate and accelerate tissue healing. Autologous serum eye drops and platelet-enriched plasma eye drops are being used in the treatment of different ophthalmological disorders. In this review, we summarize the different blood-derived formulations used in the treatment and care of ocular surface disorders. The biological basis and use of autologous serum and plasma rich in growth factors are deeply evaluated as well as the challenges to be addressed in the future in this new generation of blood-derived therapies.

• 出版日期2015-12