A Facile One-Pot Synthesis of Pyrrolo[1, 2-a] Indoles by Intramolecular 1,3-Dipolar Cycloaddition under Neat-Microwave Irradiation

作者:Hegde Subramanya; Jayashankaran Jayadevan; Ghosal Atanu; Prasanna T S R; Shivaraj Y*; Raju K Mohana
来源:Journal of Heterocyclic Chemistry, 2013, 50(2): 442-449.
DOI:10.1002/jhet.1661

摘要

A straightforward and general approach for the stereoselective synthesis of fused pyrrolo[1,2-a] indoles frameworks from>intramolecular 1,3-dipolar cycloaddition using N-alkylated BaylisHillman derivatives is presented. It was found that the cycloaddition proceeded efficiently under microwave irradiation in solvent-free condition to afford highly stereoselective cycloadducts in good yield.

  • 出版日期2013-3

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