A numerical method for obtaining an optimal temperature distribution in a 3-D triple-layered cylindrical skin structure embedded with a blood vessel

作者：Zhang L; Dai WZ^*; Nassar R

来源：Numerical Heat Transfer Part A-Applications, 2006, 49(8): 765-784.

DOI：10.1080/10407780500506691

In hyperthermia cancer treatments, the crucial problem, when heating the tumor tissue, is keeping the temperature of the normal tissue surrounding the tumor below a certain threshold so as not to cause damage to the tissue. Thus, it is important to optimize the temperature field of the entire treatment region. Recently, we have developed a numerical method for obtaining an optimal temperature distribution in a triple-layered cylindrical skin structure. In this article, we extend our method to a case involving a triple-layered cylindrical skin structure embedded with a blood vessel. The method is illustrated by a numerical example.

• 出版日期2006-5
• 单位MIT