科研之友
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摘要
An efficient method for the synthesis of perfluoroalkyl allenyl ketones via the 1,2-addition-elimination reaction of perfluoroalkyl Grignard reagents with allenoates has been established. No further reaction was observed between these perfluoroalkyl ketones and RfMgX. Under the catalysis of PdCl2 or AuCl3, perfluoroalkyl 1,2-allenyl ketones can be transformed to 2-perfluoroalkyl-substituted furans; they may also undergo 1,2-addition with organolithiums to afford tertiary 1,2-allenols containing a perfluoroalkyl group.
- 出版日期2010-1
- 单位浙江大学
