Development and Possibilities of Multichannel Voltammetric Detection in Liquid Chromatography

作者：Gonzalez Garcia Olga; Arino Cristina^*; Manuel Diaz Cruz Jose; Esteban Miquel

来源：Electroanalysis, 2011, 23(1): 140-146.

DOI：10.1002/elan.201000398

• Voltammetric detection
• Dual electrode cell
• Multichannel detection
• Multivariate calibration
• Thiols

Voltammetric detection in HPLC by using linear potential sweeps applied to dual electrode cells is evaluated. The application of an offset between both potential sweeps, applied to either serial or parallel setup of both working electrodes, and the further subtraction of the corresponding datasets are discussed. The use of multivariate curve resolution for the treatment of overlapping signals is also investigated. Despite some noise problems, mostly derived from the differences between the working electrodes, the proposed multichannel method appears to be promising. The different approaches are tested by analyzing some thiols mixtures.

• 出版日期2011-1