摘要
A new approach for the efficient construction of 1,2,3-triazole bridges as disulfide surrogates in peptides, utilizing the diaminodiacid strategy was established. Two thanatin derivatives were prepared with 1,5-and 1,4-disubstituted 1,2,3-triazole diaminodiacids as building blocks. The antibacterial activity studies are also described here.
- 出版日期2017
- 单位内蒙古科技大学包头医学院; 潍坊医学院; 中国人民解放军第二军医大学