A Review of the Expected Effects of Antimicrobials in Bovine Respiratory Disease Treatment and Control Using Outcomes from Published Randomized Clinical Trials with Negative Controls

作者：DeDonder Keith D^*; Apley Michael D

来源：Veterinary Clinics of North America: Food Animal Practice , 2015, 31(1): 97-+.

DOI：10.1016/j.cvfa.2014.11.003

• Antimicrobial drugs
• Antibiotic susceptibility
• Antibiotic resistance
• Bovine respiratory disease
• Number needed to treat
• Randomized clinical trial
• Evidence based medicine

Bovine respiratory disease (BRD) remains a major disease from an economic and an animal welfare standpoint in beef production systems. Antimicrobial administration is a mainstay in the control of and therapeutic treatment of acute BRD. Judicious use of antimicrobials remains paramount to ensure efficacy of treatment remains acceptable. A systemic review was conducted in the scientific literature, the objective of which was to present a cumulative review of the data from published randomized clinical trials using a negative control in the treatment and control of BRD and using the number needed to treat as a means to effectively convey this information to bovine practitioners.

• 出版日期2015-3