Acute-phase proteins in pregnant goats: a longitudinal study

作者：Czopowicz Michal^*; Szalus Jordanow Olga; Mickiewicz Marcin; Witkowski Lucjan; Markowska Daniel Iwona; Stefaniak Tadeusz; Reczynska Daria; Bagnicka Emilia; Kaba Jaroslaw

来源：Journal of Veterinary Diagnostic Investigation, 2017, 29(6): 814-819.

DOI：10.1177/1040638717714295

• Gestation
• haptoglobin
• pregnancy
• serum amyloid A

We documented changes in serum amyloid A (SAA) and haptoglobin (Hp) concentration in goats during pregnancy, as measured by competitive ELISAs. Fifteen does (pregnant group) and 20 castrated males (control group) were enrolled in the study. Blood samples were collected on the same day from all 35 goats, 7 times throughout the study period: at mating, then once every month, during the week preceding kidding, and 1 mo after kidding. Baseline SAA and Hp concentrations at mating were identical in the 2 groups. In the pregnant group, SAA concentration rose significantly in the second month and remained elevated until the end of pregnancy, with the peak concentration at kidding. In the control group, SAA concentration remained unchanged compared to the baseline concentration throughout the study. SAA concentration was significantly higher in the pregnant than control group only at the end of the fourth month of pregnancy and at kidding. Hp concentration did not change during pregnancy or between groups. SAA concentration at kidding was affected only by parity of does - it was highest in does in the third and fourth pregnancy and gradually lower in older does.

• 出版日期2017-11