And Then There Were None: No Need for Pluripotency Factors to Induce Reprogramming

作者：Chou Bin Kuan; Cheng Linzhao^*

来源：Cell Stem Cell, 2013, 13(3): 261-262.

DOI：10.1016/j.stem.2013.08.004

While most factors used as reprogramming transgenes can be replaced by other means, Oct4 has remained essential until now. Three recent papers have now broken this barrier through the use of opposing lineage specifying transgenes and chemical modulation, thus signifying a milestone in advancing our understanding of pluripotency induction.

• 出版日期2013-9-5