Mohs Surgery for Melanoma in Situ

作者：Kwon Soon You; Miller Stanley J^*

来源：Dermatologic Clinics, 2011, 29(2): 175-+.

DOI：10.1016/j.det.2011.01.001

• Mohs micrographic surgery
• Melanoma in situ
• Lentigo maligna
• Immunostaining
• Fresh frozen section
• Permanent paraffin section
• Peripheral margin control

Mohs micrographic surgery is a valuable option for the treatment of melanoma in situ, especially lesions of the lentigo maligna subtype that are clinically ill defined. Complete peripheral margin assessment of a tumor's borders by means of frozen or permanent sections can help reduce the surgical defect size and maximize cure rate as compared with standard excision with preset 5-mm margins. This article reviews the different variations of Mohs micrographic surgery that are currently used for melanoma in situ.

• 出版日期2011-4