Hybrid ameloblastoma and adenomatoid odontogenic tumor: report of a case and review of hybrid variations in the literature

作者：Yamazaki Manabu; Maruyama Satoshi; Abe Tatsuya; Babkair Hamzah; Fujita Hajime; Takagi Ritsuo; Koyama Jun ichi; Hayashi Takafumi; Cheng Jun; Saku Takashi^*

来源：Oral Surgery Oral Medicine Oral Pathology Oral Radiology, 2014, 118(1): E12-E18.

DOI：10.1016/j.oooo.2013.08.032

Hybrid odontogenic tumors including 2 or more different histologic types have been documented, but their occurrences are not very common. We present a case of hybrid odontogenic tumor composed of ameloblastoma and adenomatoid odontogenic tumor (AOT) arising in the mandibular molar region of a 31-year-old Japanese woman who had a history of familial adenomatous polyposis. The tumor, measuring 10 mm in diameter, was surgically removed from the alveolar bone. Histopathologically, the tumor consisted of both follicular and plexiform types of ameloblastoma in which multiple and smaller foci of AOT were intermingled. There have been 3 reported cases of hybrid ameloblastoma and AOT, all of which presented unicystic types as ameloblastoma components. This, however, is the first report of a hybrid tumor containing an authentic solid-type ameloblastoma compartment and an AOT compartment in a patient with a background of familial adenomatous polyposis.

• 出版日期2014-7