Development of Manufacturing Technology for Prolonged-Release Oral Amben Preparation

作者：Nifontova G O^*; Krechetov S P; Korostylev E V; Akhmetzyanova A R; Krasnyuk I I

来源：Pharmaceutical Chemistry Journal, 2016, 50(8): 537-542.

DOI：10.1007/s11094-016-1485-z

• hydrophobic polymer matrix
• amben
• prolonged release
• granulation

Results from technology development for manufacturing an amben prolonged-release preparation based on a Kollidon SR hydrophobic polymer matrix were presented. It was shown that dry and wet granulation could improve the processing properties of mixtures for preparing tablets and provide the required amben release kinetics.

• 出版日期2016-11