Antioxidants, Oxyrase, and mitochondrial uncoupler 2,4-dinitrophenol improved postthaw survival of rhesus monkey sperm from ejaculates with low cryosurvival

作者：Dong Qiaoxiang; Tollner Theodore L; Rodenburg Sarah E; Hill Dana L; VandeVoort Catherine A^*

来源：Fertility and Sterility, 2010, 94(6): 2359-2361.

DOI：10.1016/j.fertnstert.2010.04.017

• Electron transport
• Macaca mulatta
• reactive oxygen species
• semen

Various antioxidant strategies such as supplementation of antioxidants, limiting oxygen concentration with Oxyrase, and reducing reactive oxygen species through mild mitochondrial uncoupling had statistically significant beneficial effects on sperm cryopreservation from rhesus monkeys with low cryoresistant ejaculates. Individuals or species that have higher sensitivity to cryodamage may derive the most benefit from these treatments. (Fertil Steril (R) 2010;94:2359-61.

• 出版日期2010-11
• 单位温州医科大学