Acute kidney injury from SGLT2 inhibitors: potential mechanisms

作者:Hahn Kai; Ejaz A Ahsan; Kanbay Mehmet; Lanaspa Miguel A; Johnson Richard J*
来源:Nature Reviews Nephrology, 2016, 12(12): 711-712.
DOI:10.1038/nrneph.2016.159

摘要

SGLT2 inhibitors have shown great promise in the management of diabetes mellitus and the prevention of cardiovascular complications, but increasing evidence suggests that their use can be associated with an increased risk of acute kidney injury. Insights into the mechanisms involved might help to identify individuals who are at risk of renal injury.

  • 出版日期2016-12