Abdominal adiposity and low physical activity are independently and inversely associated with bone mineral density

作者：Krishnan Chandramouli; Choksi Palak; Peterson Mark D^*

来源：Obesity Research & Clinical Practice, 2017, 11(6): 740-746.

DOI：10.1016/j.orcp.2017.04.002

• Bone
• Physical activity
• Adiposity
• Obesity
• Epidemiology

Background and Methods: Obesity is a highly heterogeneous condition, and the link between adiposity distribution profiles and skeletal health is not well understood. This study examined the association between adiposity and bone mineral density (BMD) in a large cohort (5268 individuals) of US adults aged 20-85 years.
Results: Body mass index (BMI) and moderate-to-vigorous physical activity were positively associated with BMD. Conversely, abdominal adiposity was negatively associated with BMD, even after adjusting for age, race, BMI, and objectively-measured physical activity.
Conclusions: These findings highlight the negative influence of abdominal adiposity on BMD and contradict the notion that excess fat mass is protective for bone health.