A simple NMR analysis of the protonation equilibrium that accompanies aminoglycoside recognition: Dramatic alterations in the neomycin-B protonation state upon binding to a 23-mer RNA aptamer

作者:Freire Felix; Cuesta Igor; Corzana Francisco; Revuelta Julia; Gonzalez Carlos; Hricovini Milos; Bastida Agatha; Jimenez Barbero Jesus; Asensio Juan Luis*
来源:Chemical communications, 2007, (2): 174-176.
DOI:10.1039/b611597g

摘要

A complete characterisation of the protonation equilibrium that accompanies the molecular recognition of neomycin-B by a specific RNA receptor has been achieved by employing simple NMR measurements.

  • 出版日期2007