科研之友
微信
新浪微博
Facebook
分享链接
摘要
An efficient methodology is developed for the synthesis of functionalized specific carbazole lactams related to pyrido[4,3-b]-and quino[4,3-b] carbazole alkaloids. 3 C-C bonds and 2 rings are created in a single step via an indole-to-carbazole transformation triggered by Pd(II)-catalyzed direct C-3 alkenylation of indoles. Starting from a key pentacyclic precursor delivered by the methodology, calothrixin B is synthesized in 6 steps.
- 出版日期2018-2-21
- 单位贵州大学
