Acute Febrile Respiratory Reaction After Praziquantel Treatment During Asymptomatic Late Form of Acute Schistosomiasis

作者:Neumayr Andreas L C*; Tschirky Beatrice; Warren Ashley; Hatz Christoph F R; Blum Johannes A
来源:Journal of Travel Medicine, 2012, 19(4): 264-267.
DOI:10.1111/j.1708-8305.2012.00626.x

摘要

Paradoxical reactions (Jarish Herxheimer-like reactions) have been described in patients treated with praziquantel (PZQ) during acute schistosomiasis (infected?=?3?mo), while PZQ treatment of chronic schistosomiasis is generally considered to be safe. We report an acute febrile reaction with respiratory decompensation following PZQ treatment in a 17-year-old male patient who had no potential (re)exposure to infection for at least 5?months and was therefore considered to have reached the chronic stage of disease. We speculate that the clinical manifestations in our patient constitute a very late paradoxical reaction in an unusually long acute phase of infection.

  • 出版日期2012-7

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