Association of Lhermitte-Duclos disease and split cord malformation in a child

作者：Lahoud Georges Abi; Chalouhi Nohra; Zanaty Mario; Rizk Tony; Jabbour Pascal^*

来源：Journal of Clinical Neuroscience, 2014, 21(11): 1999-2002.

DOI：10.1016/j.jocn.2014.05.005

• Cowden syndrome
• Dysplastic cerebellar gangliocytoma
• Lhermitte-Duclos disease
• Split cord malformation

Lhermitte-Duclos disease (LDD) or cerebellar gangliocytoma is a rare pathological entity, the etiology of which remains controversial. Numerous developmental anomalies are known to be associated with LDD, but the association between LDD and split cord malformation (SCM) has not been reported to our knowledge. We report LDD in a 3-year-old girl in whom repetitive urinary tract infections led to the diagnosis of a neurogenic bladder. Thorough screening revealed a SCM at the thoracic level which was surgically repaired. The pathogenesis of this entity and management strategies are discussed in this paper.

• 出版日期2014-11