Association of increased influenza vaccination in health care workers with a reduction in nosocomial influenza infections in cancer patients

作者：Frenzel Elizabeth^*; Chemaly Roy F; Ariza Heredia Ella; Jiang Ying; Shah Dimpy P; Thomas Georgia; Graviss Linda; Raad Issam

来源：American Journal of Infection Control, 2016, 44(9): 1016-1021.

DOI：10.1016/j.ajic.2016.03.024

• Influenza
• vaccination
• health care workers
• cancer
• nosocomial infection

Background: Vaccination of health care workers (HCWs) remains a key strategy to reduce the burden of influenza infections in cancer patients.
Methods: In this 8-year study, we evaluated the effect of a multifaceted approach, including a mandatory influenza vaccination program, on HCW vaccination rates and its effect on nosocomial influenza infections in cancer patients.
Results: The influenza vaccination rate of all employees significantly increased from 56% (8,762/15,693) in 2006-2007 to 94% (17,927/19,114) in 2013-2014 (P < .0001). The 2009 mandatory participation program increased HCW vaccination rates in the targeted groups (P < .0001), and the addition of an institutional policy in 2012 requiring influenza vaccination or surgical mask use with each patient contact further increased vaccination rates by 10%-18% for all groups in 1 year. The proportion of nosocomial influenza infections significantly decreased (P = .045) during the study period and was significantly associated with increased HCW vaccination rates in the nursing staff (P = .043) and in personnel working in high-risk areas (P = .0497).
Conclusions: Multifaceted influenza vaccination programs supported by institutional policy effectively increased HCW vaccination rates. Increased HCW vaccination rates were associated with a reduction in the proportion of nosocomial influenza infections in immunocompromised cancer patients.

• 出版日期2016-9-1