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摘要
Rationale and Objectives: This study aimed to establish diffusion quantitative parameters (apparent diffusion coefficient [ADC], DDC, alpha, D-app, and K-app) in normal testes at 3.0 T. @@@ Materials and methods: Sixty-four healthy volunteers in two age groups (A: 10-39 years; B: 40 years) underwent diffusion weighted imaging scanning at 3.0 T. ADC(1000), ADC(2000), ADC(3000), DDC, a, D-app, and K-app were calculated using the mono-exponential, stretched-exponential, and kurtosis models. The correlations between parameters and the age were analyzed. The parameters were compared between the age groups and between the right and the left testes. @@@ Results: The average ADC(1000), ADC(2000), ADC(3000), DDC, alpha, D-app, and K-app, values did not significantly differ between the right and the left testes (P >.05 for all). The following significant correlations were found: positive correlations between age and testicular ADC(1000), ADC(2000), ADC(3000), DDC, and D-app (r = 0.516, 0.518, 0.518, 0.521, and 0.516, respectively; P <.01 for all) and negative correlations between age and testicular a and K-app (r = -0.363, -0.427, respectively; P <.01 for both). Compared to group B, in group A, ADC(1000), ADC(2000), ADC(3000), DDC, and D-app were significantly lower (P <.05 for all), but a and K-app were significantly higher (P <.05 for both). @@@ Conclusions: Our study demonstrated the applicability of the testicular mono-exponential, stretched-exponential, and kurtosis models. Our results can help establish a baseline for the normal testicular parameters in these diffusion models. The contralateral normal testis can serve as a suitable reference for evaluating the abnormalities of the other side. The effect of age on these parameters requires further attention.
