Adsorption-induced vesicle fission

作者：Tsai Feng Ching^*; Chen Hsuan Yi

来源：Physical Review E, 2008, 78(5): 051906.

DOI：10.1103/PhysRevE.78.051906

A theoretical model for vesicle fission induced by particle adsorption and aggregation on a membrane surface is presented. The bulk fluid contains particles that are adsorbed reversibly to the membrane. Adsorbed particles aggregate on the membrane, forming particle-rich domains. Domains at a critical size which contains n(v) particles become vesicles and leave the membrane. We find that for parameters that correspond to typical experimental situations, vesicle formation is energetically favored except for a possible energy barrier for domain nucleation at small n, where n is the number of particles in a domain. We also find that in typical experimental situations a particle-rich domain grows without being affected strongly by neighboring domains, and the vesicle formation rate is proportional to adsorption rate j(on) when j(on) is large; when j(on) is small the vesicle formation rate scales like j(on)(2). Because the diffusion flux is small for domains with small in-plane radius R(n), in the time-independent state the densities of domains with n/n(v)< 1 and 1-n/n(v)< 1 are large.

• 出版日期2008-11
• 单位中央民族大学