Mineral Trioxide Aggregate-based Sealer: Analysis of Tissue Reactions to a New Endodontic Material

作者：Scarparo Roberta Kochenborger^*; Haddad Daniel; Xavier Acasigua Gerson Arison; Medeiros Fossati Anna Cristina; Freitas Fachin Elaine Vianna; Grecca Fabiana Soares

来源：Journal of Endodontics, 2010, 36(7): 1174-1178.

DOI：10.1016/j.joen.2010.02.031

• Biocompatibility
• connective tissue
• endodontics
• mineral trioxide aggregate

Introduction: The aim of this study was to evaluate the subcutaneous connective tissue reaction to mineral trioxide aggregate (MTA)-based sealer (Endo CPM Sealer; CPM Sealer; EGEO SRL, Buenos Aires, Argentina), MTA, and an epoxy resin-based sealer (AH Plus; Dentsply HERO Industria e Comercio Ltda, Petropolis, RJ, Brazil). Methods: Polyethylene tubes containing the test materials and empty tubes (control group) were implanted in the subcutaneous tissue of 18 rats. After 7, 30, and 60 days, observations were made for cellular inflammatory components, fibrous condensation, and abscess formation. Comparisons between groups and periods of time were made using the Friedman test and the Kruskall-Wallis test. Results: Lymphocytes and plasmacytes were more intensely observed in the reaction to AH Plus sealer after 30 days (p < 0.05). MTA and the Endo CPM Sealer presented a behavior similar to that of the control group throughout the whole experiment. Conclusion: The Endo CPM Sealer presented biological potential. Characteristics of the inflammatory reaction were equivalent to those produced by MTA. (J Endod 2010;36:1174-1178)

• 出版日期2010-7