摘要
Two new ent-kaurane diterpenoids, taihangexcisoidesin C (1) and its acetonide, taihangexcisoidesin D (2), along with 9 known compounds were isolated from the leaves of isodon excisoides. The structures of the new compounds were elucidated using ID and 2D NMR spectroscopy analysis. Compounds 3-6 and 8-9 were tested for their antibacterial activity against Escherichia coli, Staphylococcus aureus, S epidermidis and S saprophyticus Compound 6 showed inhibitory effects on Staphylococcus aureus, S. epidermidis and S saprophyticus MIC values 32, 16 and 16 mu g/mL, respectively. All of the compounds didn't show effects on Escherichia colt (MIC > 10 mg/mL)
- 出版日期2010-4
- 单位新乡医学院