A triple-dimensional sensing chip for discrimination of eight antioxidants based on quantum dots and graphene

作者：Liu, Huilin; Fang, Guozhen; Deng, Qiliang; Wang, Shuo^*

来源：Biosensors and Bioelectronics, 2015, 74: 313-317.

DOI：10.1016/j.bios.2015.04.096

• Triple-dimensional
• Sensing chip
• Quantum dots
• Graphene
• Lab-on-a-nanomaterial

A triple-dimensional sensing chip is developed based on simultaneous utilization of fluorescence (FL), electrochemical (ECL) and mass-sensitivity (MS) properties of a novel nanocomposites. The sensing nanomaterial is composed of CdSe/ZnS quantum dots (QDs) and graphene through a one-pot roomtemperature reverse microemulsion polymerization. Here, full integration of QDs and graphene on one chip provides triple-dimensional sensing signals. It enables quick and accurate discrimination of eight analytes in a "lab-on-a-nanomaterial" approach and notably improves the overall sensor performance. Unknown samples randomly taken from the training set at concentrations of 0.71 mu M are successfully classified by principal component analysis (PCA) with accuracies of 92.5%, compared with the high performance liquid chromatography (HPLC) method. We further apply it to discriminate eight antioxidants from real oil samples, and explore the mechanism.

• 出版日期2015-12-15
• 单位天津科技大学