A novel synthesis route to furo[3,2-a]carbazole

作者：Xu, Mei; Fan, Tian-Yun; Zhang, Jian-Xin; Hao, Xiao-Jiang; Liu, Sheng^*

来源：Chinese Chemical Letters, 2015, 26(3): 282-284.

DOI：10.1016/j.cclet.2014.11.026

• Synthesis
• Furo[3,2-a]carbazole
• Transamination

In this paper, we report a novel approach to the heteroaryl-condensed nuclei of natural furo[3,2-a]carbazole alkaloids. Our synthetic studies use N-phthaloyl tryptophan methyl ester as starting material and zinc ion mediated transamination reaction as the key step. This work also implicated a novel strategy to assemble other [a]-fused carbazoles.

• 出版日期2015-3
• 单位贵州省中国科学院天然产物化学重点实验室; 贵州大学