Two Unusual Phenyl Derivatives from Pathogen-Infected Solanum tuberosum with Antifungal Activity

作者：Liu, Liangyan; Han, Jun; Shen, Yong; Li, Yanglu; Liu, Donglei; Guo, Huachun^*

来源：Chemistry of Natural Compounds, 2018, 54(2): 228-231.

DOI：10.1007/s10600-018-2309-z

• Solanum tuberosum
• (+)-S-solatuberol
• (+)-R-solatuberic acid
• Phytophthora infestans
• antifungal activity

Two unusual phenyl derivatives, (+)-S-solatuberol (1) and (+)-R-solatuberic acid (2), were isolated from the aerial part of potato (Solanum tuberosum) infected by the pathogenic fungus Phytophthora infestans. Their structures were identified by extensive spectroscopic analysis, including HR-MS, IR, UV, 1D/2D NMR, and quantum calculation. Compounds 1 and 2 showed moderate inhibition against P. infestans with IC50 values of 0.95 and 1.96 mM, respectively.

• 出版日期2018-3
• 单位云南农业大学