Aptamer-based cell imaging reagents capable of fluorescence switching

作者:Jung Yun Kyung; Woo Min Ah; Soh H Tom*; Park Hyun Gyu
来源:Chemical communications, 2014, 50(82): 12329-12332.
DOI:10.1039/c4cc03888f

摘要

We describe an aptamer-conjugated polydiacetylene imaging probe (ACP) that shows highly specific fluorescence switching upon binding to epithelial cancer cells that overexpress the tumor biomarker protein EpCAM (epithelial cell adhesion molecule) on their surface.

  • 出版日期2014-10-21