Anesthesiology and the cytokine network

作者：Lisowska Barbara^*; Szymanska Marta; Nowacka Elzbieta; Olszewska Malgorzata

来源：Postepy Higieny i Medycyny Doswiadczalnej, 2013, 67: 761-769.

• immune system
• cytokines
• anesthetics

The immune response is a highly specific reaction carried out by means of specialized cells that belong to the immune system. There are two types of immune response mechanisms aimed towards pathogens: non-specific, innate reactions, and specific, acquired reactions. %26lt;br%26gt;Acquired immunity, characterized by its specificity, is comprised of lymphocytes, including both T cell and B cell populations. The role of B lymphocytes is not limited to the humoral response, though the cellular immune response is carried out mainly by various T lymphocyte subpopulations. %26lt;br%26gt;The reactions of the humoral and cellular responses complement and stimulate one another mutually - cytokines are their common linking element. The attachment of cytokines to their specific receptors activates a sequence of signals - either intracellular or between the cells of various systems. %26lt;br%26gt;This organization of respective connections and reactions, including the functional relations between cells of the immune response, in its complexity, is best described as a cytokine network. %26lt;br%26gt;The response of the immune system to surgical trauma can be looked at from both a local and a general perspective. Not only surgical trauma caused by tissue damage, however, influences the functioning of the immune system, but also the drugs and techniques used during anesthesia. %26lt;br%26gt;Our article is a presentation of the effects of medications used in anesthesia with respect to their influence on the cytokine network.

• 出版日期2013-8-5