Multipurpose heterofunctional dendritic scaffolds as crosslinkers towards functional soft hydrogels and implant adhesives in bone fracture applications

作者:Hed Yvonne; Oberg Kim; Berg Sandra; Nordberg Axel; von Holst Hans; Malkoch Michael*
来源:Journal of Materials Chemistry B, 2013, 1(44): 6015-6019.
DOI:10.1039/c3tb21061h

摘要

Two sets of heterofunctional dendritic frameworks displaying an inversed and exact number of ene and azide groups have successfully been synthesized and post-functionalized with biorelevant molecules. Their facile scaffolding ability enabled the fabrication of soft and azide functional dendritic hydrogels with modulus close to muscle tissue. The dendritic scaffolds are furthermore shown to be promising primers for the development of novel bone fracture stabilization adhesives with shear strengths succeeding commercial Histroacryl (R).

  • 出版日期2013