An antifungal protein from the pea Pisum sativum var. arvense Poir

作者：Wang, H. X.; Ng, T. B.^*

来源：Peptides, 2006, 27(7): 1732-1737.

DOI：10.1016/j.peptides.2006.01.024

• Pisum sativum
• pea
• antifungal protein
• isolation

An antifungal protein with a molecular mass of 11 kDa and a lysine-rich N-terminal sequence was isolated from the seeds of the pea Pisum sativum var. arvense Poir. The antifungal protein was unadsorbed on DEAE-cellulose but adsorbed on Affi-gel blue gel and CM-cellulose. It exerted antifungal activity against Physalospora piricola with an IC50 of 0.62 mu M, and also antifungal activity against Fusarium oxysporum and Mycosphaerella arachidicola. It inhibited human immunodeficiency virus type 1 reverse transcriptase with an IC50 of 4.7 mu M.

• 出版日期2006-7
• 单位农业生物技术国家重点实验室; 香港中文大学; 中国农业大学