A Case of Fibroelastolytic Papulosis on the Neck of a Young Man

作者：Song Young Chan; Oh Byung Ho; Ko Jong Hyun; Kim Ji Young; Hwang Young Ji; Lee Yang Won^*; Choe Yong Beom; Ahn Kyu Joong; Song Kyae Yong

来源：Annals of Dermatology, 2011, 23(2): 193-197.

DOI：10.5021/ad.2011.23.2.193

• Elastolysis
• Fibroelastolytic papulosis

Fibroelastolytic papulosis of the neck (FEPN) encompasses a spectrum of two disorders that were previously reported as pseudoxanthoma elasticum-like papillary dermal elastolysis (PXE-PDE) and white fibrous papulosis of the neck (WFPN). The clinical presentation of FEPN is asymptomatic to mildly pruritic whitish-yellow papules that may coalesce into cobblestone patterned plaques that resemble pseudoxanthoma elasticum (PXE). The histology is characterized by a decrease or loss of elastic fibers in the papillary dermis and this is sometimes accompanied by a minimal or nodular increase of dermal collagen fibers. We report here on a 28-year-old Korean man with asymptomatic, multiple, skin-colored to slightly yellowish, match-head sized, cobblestone-patterned papules on the neck, and these were histologically consistent with FEPN and the papules showed slightly increased dermal collagen associated with decreased and fragmented elastic fibers, elastin and tropoelastin. The pathogenesis of FEPN in this case might have been related with mild dermal inflammation, followed by fragmentation, elastolysis and increased dermal collagen. (Ann Dermatol 23(2) 193 similar to 197, 2011)

• 出版日期2011-5