Zwitterionic fluorescent nanoparticles prepared using BODIPY conjugated polysulfobetaines for cancer cell imaging

作者:Mosaiab Tamim; Shin Chun im; Choi Pyeong Ho; Shin Gyo Jic; Lee Sangkug; Choi Kyung Ho; Yoo Eui Sang; Lee Jihoon; In Insik*; Park Sung Young
来源:New Journal of Chemistry, 2013, 37(12): 3845-3848.
DOI:10.1039/c3nj00941f

摘要

Zwitterionic fluorescent nanoparticles are developed by using polysulfobetaine methacrylate, NIPAAm and BODIPY fluorophores to identify the cancer cells in response to intra and extracellular stimuli. The fluorescent nanoparticles exhibit minimal fluorescence intensity at physiological temperature and pH, while strong emissions are observed in acidic and basic environments enabling the nanoparticles to act as novel fluorescence probes.

  • 出版日期2013