A case of steroid-dependent myeloid granulocytic sarcoma masquerading as Crohn's disease

作者:Kwan Lola Y; Targan Stephan R; Shih David Q*
来源:World Journal of Gastroenterology, 2011, 17(19): 2446-2449.
DOI:10.3748/wjg.v17.i19.2446

摘要

Small bowel tumors and Crohn's disease are common causes of small bowel obstruction. Early stage neoplasms can easily be mistaken for Crohn's disease. Therefore, thorough work-ups including imaging studies and endoscopic evaluation with biopsies are critical for accurate diagnosis. Here we report a case of an otherwise healthy female with progressive onset of multiple, recurrent obstructive symptoms secondary to terminal ileal narrowing who was referred for management of steroid-dependent Crohn's disease. After thorough evaluation, the diagnosis was revised to myeloid granulocytic sarcoma involving the terminal ileum. In this case, a delay in diagnosis can be detrimental for prognosis, as myeloid granulocytic sarcoma is highly predictive of underlying acute myeloid leukemia and needs urgent referral for chemotherapy and/or resection.

  • 出版日期2011-5-21