A new route to naphthyl ketones via copper-mediated intramolecular aerobic oxidative cyclization of alkynes and sulfonylcrotonates

作者：Wang, Zhi-Qiang^*; Xu, Kun; Zhang, Xu; Li, Ting; Zheng, Shao-Long; Yu, Lin-Tao; Mao, Wu-Tao; Chen, Chang-Zhong; Wang, Li-Ya^*

来源：RSC Advances, 2016, 6(106): 103919-103922.

DOI：10.1039/c6ra23244b

• POLYSUBSTITUTED NAPHTHALENE DERIVATIVES
• 3+3 BENZANNULATION REACTIONS
• REGIOSELECTIVE SYNTHESIS
• ALPHA,BETA-UNSATURATED ALDEHYDES
• SUBSTITUTED NAPHTHALENES
• EFFICIENT SYNTHESIS
• CONCISE SYNTHESIS
• FACILE METHOD
• IN-SITU
• C-C

Herein we report a copper-mediated intramolecular aerobic oxidative cyclization of alkynes and sulfonylcrotonates. This method provides simple, efficient and easy to operate access to a variety of highly functionalized naphthyl ketones with excellent functional group tolerance.

• 出版日期2016
• 单位南阳师范学院