Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

作者:Yen Chun Wan; de Puig Helena; Tam Justina O; Gomez Marquez Jose; Bosch Irene; Hamad Schifferli Kimberly*; Gehrke Lee
来源:Lab on a Chip, 2015, 15(7): 1638-1641.
DOI:10.1039/c5lc00055f

摘要

Rapid point-of-care (POC) diagnostic devices are needed for field-forward screening of severe acute systemic febrile illnesses. Multiplexed rapid lateral flow diagnostics have the potential to distinguish among multiple pathogens, thereby facilitating diagnosis and improving patient care. Here, we present a platform for multiplexed pathogen detection using multi-colored silver nanoplates. This design requires no external excitation source and permits multiplexed analysis in a single channel, facilitating integration and manufacturing.