alpha-2 beta-Adrenoreceptor Gene Polymorphism in Patients With Disorders of Cardiac Conduction

作者：Chernova A A^*; Nikulina S Yu; Tretyakova S S; Maximov V N; Voevoda M I; Chernov V N

来源：Kardiologiya, 2013, 53(7): 45-49.

• alpha-2 beta-adrenoreceptor gene
• atrioventriculaar block
• sick sinus node syndrome

The article is devoted to the role of insertion-deletion polymorphism of alpha-2 beta-adrenoreceptor gene in development of hereditary disorders of cardiac conduction. We examined 71 patients with atrioventricular blocks and 92 patients with sick sinus node syndrome. Statistically significant preponderance of homozygous genotype DD of ADRA2B gene was found in both groups. Associations of alleles with male or female gender were also revealed.

• 出版日期2013