A population-based study comparing HRQoL among breast, prostate, and colorectal cancer survivors to propensity score matched controls, by cancer type, and gender

作者：LeMasters Traci^*; Madhavan Suresh; Sambamoorthi Usha; Kurian Sobha

来源：Psycho-Oncology, 2013, 22(10): 2270-2282.

DOI：10.1002/pon.3288

• cancer
• oncology
• health-related quality of life
• gender differences
• case-control

BackgroundObjectives were to compare health-related quality of life (HRQoL) between breast cancer survivors, prostate cancer survivors (PCS), and colorectal cancer survivors (CCS) to matched controls, stratified by short and long-term survivors, by cancer type, and gender. %26lt;br%26gt;MethodsBy using the 2009 Behavioral Risk Factor Surveillance System, propensity scores matched three controls to adult survivors %26gt;1year past diagnosis (N=11,964) on age, gender, race/ethnicity, income, insurance status, and region of the USA Chi-square tests and logistic regression models compared HRQoL outcomes (life satisfaction, activity limitations, sleep quality, emotional support, general, physical, and mental health). %26lt;br%26gt;ResultsAlthough all cancer survivors reported worse general health (p%26lt;0.000) and more activity limitations (p%26lt;0.004) than controls, these disparities decreased among long-term survivors. Short-term PCS and male CCS were more likely to report worse outcomes across additional domains of HRQoL than controls, but PCS were 0.61, 0.63, and 0.70 times less likely to report activity limitations, fair/poor general health, and 1-15 bad physical health days in the past month than male CCS. Breast cancer survivors and female CCS were 2.12 and 3.17, 1.58 and 1.86, and 1.49 and 153, respectively, times more likely to report rarely/never receiving needed emotional support, 1-15 bad mental health days in the past month, and not receiving enough sleep 1-15days in the past month than PCS and male CCS. %26lt;br%26gt;ConclusionsCancer survivors experience worse HRQoL than similar individuals without a history of cancer and the severity of affected HRQoL domains differ by time since diagnosis, cancer type, and gender.

• 出版日期2013-10