A Feasibility Study Regarding the Potential Use of Silica-Doped Calcium Sulfate Anhydrite as a Bone Void Filler

作者:Chang Man Ping; Hsu Hsiu Ching; Tuan Wei Hsing*; Lai Po Liang*
来源:Journal of Medical and Biological Engineering, 2017, 37(6): 879-886.
DOI:10.1007/s40846-017-0253-1

摘要

In the present study, the feasibility of using calcium sulfate anhydrite (CaSO4) pellets as bone void filler is evaluated. The calcium sulfate anhydrite pellets are prepared by dry-pressing calcium sulfate hemihydrate powder, then sintering at elevated temperatures. The remaining porosity within anhydrite pellets is only 7% after sintering at 1000 A degrees C. The growth of CaSO4 grains during sintering is very fast. The addition of a small amount of silica (SiO2), < 1 wt%, can prevent the coarsening of anhydrite grains during sintering. The microstructure refinement may be related to the formation of CaSiO3 particles at the boundaries of the CaSO4 grains. The SiO2-doped anhydrite pellets thus exhibit higher compressive strength. Moreover, the degradation of SiO2-doped anhydrite pellets is slower than that of anhydrite pellets. The slow degradation rate is likely attributable to the dissolution of minute amounts of SiO2 in CaSO4.

  • 出版日期2017-12
  • 单位长春大学