A silver(I)-catalyzed intramolecular Ficini's [2+2] cycloaddition employing ynamides

作者：Wang Xiao Na^*; Ma Zhi Xiong; Deng Jun; Hsung Richard P

来源：Tetrahedron Letters, 2015, 56(23): 3463-3467.

DOI：10.1016/j.tetlet.2015.01.017

• Intramolecular [2+2] cycloaddition
• Ynamides
• The Ficini reaction
• AgNTf2
• Electrocyclic ring-opening

An intramolecular [2+2] cycloaddition using N-sulfonyl substituted ynamides tethered to an enone motif is described here. This thermally driven [2+2] cycloaddition manifold can be catalyzed effectively using AgNTf2, and represents the first examples of an intramolecular Ficini reaction. Published by Elsevier Ltd.

• 出版日期2015-6-3
• 单位郑州大学; 天津大学