A Simple, Diversity Oriented Synthesis of Highly Substituted Pyridines

作者:Kaczanowska Katarzyna; Eickhoff Holger; Albert Klaus; Wiesmueller Karl Heinz; Schaffner Arnaud Pierre*
来源:Journal of Heterocyclic Chemistry, 2011, 48(4): 792-798.
DOI:10.1002/jhet.614

摘要

A particularly straightforward and efficient protocol for the synthesis of highly substituted pyridines, based on a condensation reaction of beta-aminocrotonitrile and easily accessible (E)-2-oxo-4-aryl-but-3-enoic acids and (E)-4-oxo-4-aryl-but-2-enoic acids is described.

  • 出版日期2011-7