Down Syndrome and Thyroid Function

作者：Graber Evan^*; Chacko Elizabeth; Regelmann Molly O; Costin Gertrude; Rapaport Robert

来源：Endocrinology and Metabolism Clinics of North America, 2012, 41(4): 735-+.

DOI：10.1016/j.ecl.2012.08.008

• Down syndrome
• Thyroid function
• Euthyroidism
• Hypothyroidism

Thyroid dysfunction in children with Down syndrome (DS) can occur as early as birth. As children with DS age, their risk for thyroid autoimmunity manifested as autoimmune hypothyroidism or Graves disease increases. The optimal timing and method for thyroid screening in children with DS remains controversial. The American Academy of Pediatrics recommends annual screening in this population. Consensus is needed to establish working definitions of euthyroidism and mild hypothyroidism in all infants, but especially in those with DS.

• 出版日期2012-12