Macrocyclic dinuclear nickel(II) and manganese(II) complexes: synthesis, X-ray crystal structures, DNA cleavage, and antimicrobial activity studies

作者：Cheng, Q. R.; Yu, L.; Li, P.; Liao, G. Y.; Zhou, H.^*; Pan, Z. Q.

来源：Transition Metal Chemistry, 2015, 40(8): 789-797.

DOI：10.1007/s11243-015-9973-7

• SCHIFF-BASE
• MAGNETIC-PROPERTIES
• COPPER(II) COMPLEXES
• BINUCLEAR COPPER(II)
• PENDANT-ARMS
• LIGAND
• COORDINATION

Three dinuclear macrocyclic complexes, [Ni2L1(mu-OAc)(H2O)(CH3O)](ClO4)(2)center dot 4(H2O) (1), [Mn2L2(mu-OAc) (H2O)]ClO4 center dot H2O (2) and [Mn2L3(mu-OAc)]ClO4 center dot H2O (3), (where H2L1, H2L2 and H2L3 are the [2 + 2] condensation products of 2,6-diformyl-4-fluorophenol with diethylenetriamine and N,N-bis(3-aminopropyl)-2-thiopheno-ethylamine, respectively), have been synthesized and characterized. The electrochemical characteristics showed that the metal centers are more electropositive when strongly electron-withdrawing groups are attached to the macrocyclic ring, and hence more easily reduced. All three complexes have been found to promote cleavage of plasmid pBR322 DNA from the supercoiled form I to the open circular form II. The antibacterial activities of the complexes were also studied.

• 出版日期2015-11
• 单位武汉工程大学; 中国地质大学（北京）