Adherence to Phosphate Binder Therapy Is the Primary Determinant of Hyperphosphatemia Incidence in Patients Receiving Peritoneal Dialysis

作者：Hung Kai Yin; Liao Shang Chih; Chen Tzu Hsiu; Chao Mei Chen; Chen Jin Bor^*

来源：Therapeutic Apheresis and Dialysis, 2013, 17(1): 72-77.

DOI：10.1111/j.1744-9987.2012.01098.x

• Adherence
• Chronic kidney disease
• Hyperphosphatemia
• Peritoneal dialysis
• Phosphate binders

We investigated the major determinant of hyperphosphatemia incidence among patients receiving peritoneal dialysis. Seventy-six patients aged 2555years who had received peritoneal dialysis for more than 3months were recruited. The patients were divided into three groups according to their serum phosphorus levels (Group 1, 6mg/dL; Group 2, 5.94.8mg/dL; and Group 3, %26lt;4.8mg/dL). Renal dietitians interviewed the patients to determine their phosphate intake and adherence to phosphate binder therapy. No statistical differences in demographics or phosphate intake were identified among the groups. However, adherence to phosphate binders was greater in Group 3 than in Groups 1 and 2 (96.3% vs. 21.4% and 52.4%, respectively; P %26lt; 0.001). Multivariate analysis showed that adherence to phosphate binder therapy was the only significant contributor to serum phosphorus levels (P= 0.0001). Adherence to diet was better than adherence to phosphate binder therapy among patients receiving peritoneal dialysis, and the latter determined the incidence of hyperphosphatemia.

• 出版日期2013-2
• 单位长春大学